Men looking to lose stubborn fat and boost energy need weight loss supplements that support their unique biology. This article rounds up the best weight loss supplements for men in 2025, including muscle-friendly thermogenics, stimulant-free options, and metabolism boosters. Products like Instant Knockout and Burn Lab Pro are featured alongside ProZenith for men who want results without sacrificing health. Learn which ingredients to look for, how to use them, and where to buy safely online.